Er Zhi Wan, Two-Ultimate Pill, pairs Nu Zhen Zi with Han Lian Cao. The catalogue classes it among the formulas that nourish and tonify Yin, and records it as feeding the Yin and Blood of the Liver and Kidneys and cooling the Blood to stop bleeding.

Herb

Amount

nu zhen zi

—

han lian cao

—

Actions and indications

Nourishes the Yin and Blood of the Kidneys and Liver

Liver and Kidney Yin deficiency, sometimes with deficiency Heat and bleeding
Sore, weak lower back and knees; weak or wasting legs
Dizziness, ringing in the ears and blurry vision
Hair that greys or falls out too early
Dry, parched mouth and throat, with a bitter taste
Poor, dream-filled sleep and restlessness
Nocturnal emissions or spermatorrhoea
Tongue red and dry with scant or absent coat; pulse thin and rapid

Cools the Blood and stops bleeding

Bleeding pushed out by Yin deficiency Heat, such as blood in the urine, abnormal uterine bleeding or heavy periods

Modern uses

Menopausal complaints
Post-menopausal uterine bleeding
Menorrhagia
Metrorrhagia
Prolonged menstruation
Threatened miscarriage
Premature ovarian failure, prevention
Haemorrhage
Haemoptysis
Haematochezia
Haematuria
Aplastic anaemia
Leukopenia
Thrombocytopenia
Hepatitis B
Chronic hepatitis
Chronic nephritis
Prostatitis
Spermatorrhoea
Nocturnal emissions
Coronary heart disease
Palpitations
Neurasthenia
Insomnia
Dizziness
Dizziness and blurry vision in older people
Tourette syndrome
Alopecia
Prematurely grey hair
Lumbago
Painful obstruction
Obesity
Hyperglycaemia
Constipation

Modifications

A stronger effect: + sang shen

Dizziness and blurred vision: + gou qi zi, + ju hua

Marked bleeding, with cooling herbs that stop bleeding added

Chronic nephritis, Liver and Kidney Yin deficiency with Blood Heat (combined with Qi Ju Di Huang Wan)

Chronic nephritis as above, with severe Yin deficiency (combined with Qi Ju Di Huang Wan): + gui ban, + mai men dong

Chronic nephritis as above, with Liver Yang rising (combined with Qi Ju Di Huang Wan): + long dan cao, + xia ku cao

Chronic nephritis with Blood Heat where both Yin and Yang of Liver and Kidneys are deficient (combined with Qi Ju Di Huang Wan): + xian mao, + yin yang huo

Aplastic anaemia, Qi and Yin deficiency: + ren shen, + e jiao, + huang qi

Aplastic anaemia, Yin of Liver and Kidneys depleted: + shu di huang, + tu si zi, + dang gui

Hepatitis B, Damp-Heat, with Qi tonics added if needed: + yin chen hao, + tu fu ling, + chui pen cao

Hepatitis B, Heat: + ban lan gen, + pu gong ying

Hepatitis B, poor appetite: + ji nei jin, + gu ya

Show all 50 modifications

Hepatitis B, constipation: + da huang, + hu zhang
Threatened miscarriage: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang
Threatened miscarriage, Qi deficient: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang, + tai zi shen, + huang qi
Threatened miscarriage, Yang deficient: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang
Threatened miscarriage, Yin deficient: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang, + sheng di huang, + sang ye, + huang qin, + zhu ru
Threatened miscarriage, Blood deficient: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang, + gou qi zi, + lǜ dòu yī
Threatened miscarriage, Qi stagnant: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang, + mu xiang, + sha ren
Threatened miscarriage, heavy bleeding: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang, + duan long gu, + mu li, + xue yu tan
Threatened miscarriage, dry stools and constipation: + du zhong, + sang ji sheng, + huo xiang, + zi su geng, + lu jiao shuang, + xuan shen, + huo ma ren, + qian hu
Prostatitis (combined with Liu Wei Di Huang Wan): + sheng di huang, + tu fu ling, + bei xie
Prostatitis, getting up at night to urinate and seminal emission (combined with Liu Wei Di Huang Wan): + sheng di huang, + tu fu ling, + bei xie, + jin ying zi, + qian shi, + wu wei zi
Prostatitis, Qi deficient (combined with Liu Wei Di Huang Wan): + sheng di huang, + tu fu ling, + bei xie, + huang qi, + bai zhu
Prostatitis, nodules on the prostate (combined with Liu Wei Di Huang Wan): + sheng di huang, + tu fu ling, + bei xie, + li zhi he, + ju he, + ji nei jin
Prostatitis, Kidney Yang deficient (combined with Liu Wei Di Huang Wan): + sheng di huang, + tu fu ling, + bei xie, + rou gui, + yin yang huo, + ba ji tian
Prostatitis, difficult, burning urination (combined with Liu Wei Di Huang Wan): + sheng di huang, + tu fu ling, + bei xie, + che qian zi
Prostatitis, restless with poor sleep (combined with Liu Wei Di Huang Wan): + sheng di huang, + tu fu ling, + bei xie, + yuan zhi, + shi chang pu, + fu shen
Menopausal syndrome, Kidney and Liver Yin deficient with Liver Yang rising (combined with Zuo Gui Yin): + shi jue ming, + yu jin, + bai shao
Infertility (combined with Yang Jing Zhong Yu Tang)
Infertility with blazing deficiency Fire: thinness, hot palms, soles and chest, recurring afternoon fever (combined with Yang Jing Zhong Yu Tang): + mu dan pi, + di gu pi, + huang bai, + gui ban
Infertility where Blood is insufficient and periods are light and pale, other Blood tonics optional (combined with Yang Jing Zhong Yu Tang): + lu jiao jiao, + zi he che
Tourette syndrome (combined with Da Ding Feng Zhu)
Prolonged periods (combined with Liang Di Tang)
Preventing premature ovarian failure where Heart and Kidneys fail to communicate (combined with Huang Lian E Jiao Tang)
Hair loss (combined with Zuo Gui Yin): + zhi he shou wu, + zi he che, + e jiao
Combined with Gui Shen Wan (placement in the source unclear)
Coronary heart disease, Heart and Kidney Yin deficiency (combined with Yi Guan Jian): + dan shen, + mu dan pi, + chuan niu xi, + mu li
Coronary heart disease as above, severe pain (combined with Yi Guan Jian): + dan shen, + mu dan pi, + chuan niu xi, + mu li, + chen xiang, + chuan xiong
Coronary heart disease as above, heavy night sweats (combined with Yi Guan Jian): + dan shen, + mu dan pi, + chuan niu xi, + mu li, + zhi mu, + huang bai, + di gu pi
Coronary heart disease as above, marked palpitations and insomnia (combined with Yi Guan Jian): + dan shen, + mu dan pi, + chuan niu xi, + mu li, + suan zao ren, + bai zi ren
Coronary heart disease as above, high-pitched ringing in the ears (combined with Yi Guan Jian): + dan shen, + mu dan pi, + chuan niu xi, + mu li, + shi jue ming, + gou teng
Coronary heart disease as above, high-pitched ringing in the ears, second version (combined with Yi Guan Jian): + dan shen, + mu dan pi, + chuan niu xi, + mu li, + dang shen, + zhi gan cao
Fibrocystic breasts, Chong and Ren disharmony (combined with Xiao Yao San and Er Xian Tang)
Fibrocystic breasts, Chong and Ren disharmony, hard lumps (combined with Xiao Yao San and Er Xian Tang): + yu jin, + e zhu, + hai zao
Fibrocystic breasts, Chong and Ren disharmony, nipple discharge (combined with Xiao Yao San and Er Xian Tang): + mu dan pi, + zhi zi, + han lian cao
Bleeding after menopause, with anxiety, short temper, flank pain, bitter taste, red face, fever, sweating and emotional swings: + gui ban, + yu jin
Bleeding after menopause, Kidney Yin and Yang deficient (combined with Zuo Gui Yin): + shu di huang
Bleeding after menopause, Kidney Yin and Yang deficient, with insomnia (combined with Zuo Gui Yin): + shu di huang, + ye jiao teng, + zhen zhu
Bleeding after menopause, Kidney Yin and Yang deficient, with lumbar pain (combined with Zuo Gui Yin): + shu di huang, + xu duan, + bu gu zhi

Cautions

contraindication Atrophy disorder caused by an invasion of Damp-Heat

contraindication Unsuitable for cough, exterior conditions, and patterns of excess or Damp

caution Use carefully when digestion is weak

caution Spleen and Stomach deficiency with Cold or Damp: its rich, cooling herbs can worsen poor appetite, loose stools or a stuffy, full feeling, so use with caution or modify; Han Lian Cao is cold and can loosen the bowels

Pinyin

er zhi wan

English Name

Two-Ultimate Pill

er zhi wan

About er zhi wan

Ingredients

Actions and indications

Nourishes the Yin and Blood of the Kidneys and Liver

Cools the Blood and stops bleeding

Modern uses

Symptoms

Modifications

Cautions

Preparation

Names

Classification